HCK 抗体 (C-Term)
-
- 抗原 See all HCK 抗体
- HCK (Hemopoietic Cell Kinase (HCK))
-
抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠, 豚鼠, 马, 兔, Cow, 犬
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This HCK antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- LVKLHAVVTK EPIYIITEFM AKGSLLDFLK SDEGSKQPLP KLIDFSAQIA
- 预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against HCK. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human HCK
- Top Product
- Discover our top product HCK Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 504 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- HCK (Hemopoietic Cell Kinase (HCK))
- 别名
- HCK (HCK 产品)
- 别名
- laloo antibody, HCK antibody, MGC107870 antibody, JTK9 antibody, p59Hck antibody, p61Hck antibody, AI849071 antibody, Bmk antibody, Hctk antibody, p56Hck antibody, HCK proto-oncogene, Src family tyrosine kinase L homeolog antibody, HCK proto-oncogene, Src family tyrosine kinase antibody, hemopoietic cell kinase antibody, hck.L antibody, HCK antibody, hck antibody, Hck antibody
- 背景
-
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.
Alias Symbols: JTK9, p59Hck, p61Hck
Protein Interaction Partner: NOTCH2NL, KRTAP10-9, KRT40, GOPC, MTUS2, SPRR2A, STAT3, ACTB, Mbp, MED28, RUFY1, WNT2, HSP90AA1, ERBB3, ABL2, CBL, APP, PAK2, nef, TNK2, ADAM15, CREBBP, FASLG, SH3KBP1, KHDRBS1, MYC, UBC, SRC, MAP4K5, CHST15, ELMO1, SF3B3, EVL, IRF2BPL, SH3BP1, INPP5D, AG
Protein Size: 504 - 分子量
- 55 kDa
- 基因ID
- 3055
- NCBI登录号
- NM_001172131, NP_001165602
- UniProt
- P08631
- 途径
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
-