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VASP 抗体 (C-Term)

The 兔 多克隆 anti-VASP antibody (ABIN2788720) specifically detects VASP in WB. The antibody is reactive with 人, 小鼠, 大鼠, 犬, Cow, 马 和 豚鼠 samples.
产品编号 ABIN2788720
发货至: 中国
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Quick Overview for VASP 抗体 (C-Term) (ABIN2788720)

抗原

See all VASP 抗体
VASP (Vasodilator-Stimulated phosphoprotein (VASP))

适用

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人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠

宿主

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克隆类型

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多克隆

标记

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This VASP antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    SGRSGGGGLM EEMNAMLARR RKATQVGEKT PKDESANQEE PEARVPAQSE

    预测反应

    Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 79%, Rat: 86%

    产品特性

    This is a rabbit polyclonal antibody against VASP. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human VASP
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 380 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    VASP (Vasodilator-Stimulated phosphoprotein (VASP))

    别名

    VASP

    背景

    Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
    Alias Symbols: -
    Protein Interaction Partner: ABI3, FGFR1OP, ABI2, SCGB2A2, CEP250, TP53, XIRP1, UBC, FAT1, FOXK1, PPP4R2, PAAF1, PRPF40A, RPP38, PRMT5, POP7, CUL4B, PSMA5, DDB1, APBB1, YWHAQ, NR4A1, YWHAE, DMRTB1, NPM1, VCAM1, SAT1, ITGA4, FN1, AMOT, SF3B2, SF3A3, ATP6V1F, CPNE3, SRSF9, UBE2N, UAP1,
    Protein Size: 380

    分子量

    42 kDa

    基因ID

    7408

    NCBI登录号

    NM_003370, NP_003361

    UniProt

    P50552

    途径

    TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
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