Endothelin 3 抗体 (C-Term)
Quick Overview for Endothelin 3 抗体 (C-Term) (ABIN2788707)
抗原
See all Endothelin 3 (EDN3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- LHFCTQTLDV SSNSRTAEKT DKEEEGKVRG ANRGLCQRRL KSRTNKASRL
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预测反应
- Human: 100%, Pig: 85%
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产品特性
- This is a rabbit polyclonal antibody against EDN3. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human EDN3
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anti-Endothelin 3 (EDN3) (AA 1-238) antibody
EDN3 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2A6-2A4 unconjugated
anti-Endothelin 3 (EDN3) antibodyEDN3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Endothelin 3 (EDN3) (AA 1-238) antibodyEDN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Endothelin 3 (EDN3) (C-Term) antibodyEDN3 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Endothelin 3 (EDN3) (AA 20-167) antibodyEDN3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Endothelin 3 (EDN3) (AA 1-238) antibodyEDN3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Endothelin 3 (EDN3) antibodyEDN3 适用: 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Endothelin 3 (EDN3) (AA 1-238) antibodyEDN3 适用: 人 WB, ELISA, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 2A6-2A4 unconjugated
anti-Endothelin 3 (EDN3) (AA 17-187) antibodyEDN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Endothelin 3 (EDN3) antibodyEDN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 219 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Endothelin 3 (EDN3)
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别名
- EDN3
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背景
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The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.
Alias Symbols: ET3, MGC15067, MGC61498, ET-3, WS4B, HSCR4, PPET3
Protein Interaction Partner: EDNRB, EDNRA, CMA1, CTSE, KEL,
Protein Size: 219 -
分子量
- 24 kDa
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基因ID
- 1908
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NCBI登录号
- NM_207032, NP_996915
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UniProt
- P14138
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途径
- Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
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