Hexosaminidase A 抗体 (C-Term)
Quick Overview for Hexosaminidase A 抗体 (C-Term) (ABIN2788673)
抗原
See all Hexosaminidase A (HEXA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- WKDFYIVEPL AFEGTPEQKA LVIGGEACMW GEYVDNTNLV PRLWPRAGAV
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预测反应
- Cow: 93%, Dog: 85%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%, Sheep: 93%
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产品特性
- This is a rabbit polyclonal antibody against HEXA. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human HEXA
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anti-Hexosaminidase A (HEXA) (AA 318-529) antibody
HEXA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hexosaminidase A (HEXA) (Internal Region) antibodyHEXA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hexosaminidase A (HEXA) (AA 1-529) antibodyHEXA 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3D1 unconjugated
anti-Hexosaminidase A (HEXA) antibodyHEXA 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3F10 unconjugated
anti-Hexosaminidase A (HEXA) (AA 142-170), (N-Term) antibodyHEXA 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20977 unconjugated
anti-Hexosaminidase A (HEXA) (AA 1-529) antibodyHEXA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D1 unconjugated
anti-Hexosaminidase A (HEXA) antibodyHEXA 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal unconjugated
anti-Hexosaminidase A (HEXA) (AA 319-528) antibodyHEXA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hexosaminidase A (HEXA) (AA 89-529) antibodyHEXA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hexosaminidase A (HEXA) antibodyHEXA 适用: 人 WB, FACS, EIA 宿主: 小鼠 Monoclonal 3F10 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 529 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Hexosaminidase A (HEXA)
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别名
- HEXA
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背景
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This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).
Alias Symbols: MGC99608, TSD
Protein Interaction Partner: H2AFV, WDR61, UBA6, UBR7, C9orf78, HERC4, FKBP9, PDCD10, NUBP2, GTF3C4, HIST1H2BO, XPNPEP1, EZR, RAD23A, PCNA, KTN1, HK1, GDI1, CAPZB, AHCY, ACAT2, FBXO6, H2AFX, GM2A, USP22,
Protein Size: 529 -
分子量
- 48 kDa
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基因ID
- 3073
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NCBI登录号
- NM_000520, NP_000511
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UniProt
- P06865
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途径
- Sensory Perception of Sound, Glycosaminoglycan Metabolic Process
抗原
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