Vinculin 抗体 (C-Term)
Quick Overview for Vinculin 抗体 (C-Term) (ABIN2788672)
抗原
See all Vinculin (VCL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- PRPPPPEEKD EEFPEQKAGE VINQPMMMAA RQLHDEARKW SSKGNDIIAA
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against VCL. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human VCL
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1066 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Vinculin (VCL)
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别名
- VCL
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背景
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Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
Alias Symbols: CMD1W, CMH15, MVCL
Protein Interaction Partner: VCL, UBC, TEKT1, SUMO2, ASB7, CTPS1, GINS3, UBFD1, ISOC1, DCPS, ERP44, PDCD10, FERMT2, YWHAQ, TUBB3, PDIA4, STK24, YWHAZ, YWHAH, YWHAG, YWHAE, XPO1, SNRPF, RAP1GDS1, PPP5C, PPP1R2, PFAS, PDHA1, MSN, HSPA9, HSPA5, GSS, SFN, GNAI3, G6PD, EIF5, ECHS1, TBCB,
Protein Size: 1066 -
分子量
- 117 kDa
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基因ID
- 7414
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NCBI登录号
- NM_003373, NP_003364
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UniProt
- P18206
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途径
- Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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