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Vinculin 抗体 (C-Term)

This anti-Vinculin antibody is a 兔 多克隆 antibody detecting Vinculin in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 兔, Cow, 马, 斑马鱼, 犬 和 豚鼠.
产品编号 ABIN2788672
发货至: 中国

Quick Overview for Vinculin 抗体 (C-Term) (ABIN2788672)

抗原

See all Vinculin (VCL) 抗体
Vinculin (VCL)

适用

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人, 小鼠, 大鼠, 兔, Cow, 马, 斑马鱼, 犬, 豚鼠

宿主

  • 99
  • 53
  • 1

克隆类型

  • 86
  • 67
多克隆

标记

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This Vinculin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    • 1
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    C-Term

    序列

    PRPPPPEEKD EEFPEQKAGE VINQPMMMAA RQLHDEARKW SSKGNDIIAA

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against VCL. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human VCL
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1066 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Vinculin (VCL)

    别名

    VCL

    背景

    Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
    Alias Symbols: CMD1W, CMH15, MVCL
    Protein Interaction Partner: VCL, UBC, TEKT1, SUMO2, ASB7, CTPS1, GINS3, UBFD1, ISOC1, DCPS, ERP44, PDCD10, FERMT2, YWHAQ, TUBB3, PDIA4, STK24, YWHAZ, YWHAH, YWHAG, YWHAE, XPO1, SNRPF, RAP1GDS1, PPP5C, PPP1R2, PFAS, PDHA1, MSN, HSPA9, HSPA5, GSS, SFN, GNAI3, G6PD, EIF5, ECHS1, TBCB,
    Protein Size: 1066

    分子量

    117 kDa

    基因ID

    7414

    NCBI登录号

    NM_003373, NP_003364

    UniProt

    P18206

    途径

    Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
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