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CD13 抗体 (N-Term)

This anti-CD13 antibody is a 兔 多克隆 antibody detecting CD13 in WB. Suitable for 人, 大鼠, 马, 豚鼠, 犬 和 兔.
产品编号 ABIN2788665
发货至: 中国

Quick Overview for CD13 抗体 (N-Term) (ABIN2788665)

抗原

See all CD13 (ANPEP) 抗体
CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

适用

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人, 大鼠, 马, 豚鼠, 犬, 兔

宿主

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克隆类型

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多克隆

标记

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This CD13 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    VGGSQPPDID KTELVEPTEY LVVHLKGSLV KDSQYEMDSE FEGELADDLA

    预测反应

    Dog: 79%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Rabbit: 79%, Rat: 79%

    产品特性

    This is a rabbit polyclonal antibody against ANPEP. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ANPEP
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 967 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

    别名

    ANPEP

    背景

    Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.
    Alias Symbols: APN, CD13, GP150, LAP1, P150, PEPN
    Protein Interaction Partner: UBC, ANPEP, Cep76, TM4SF1,
    Protein Size: 967

    分子量

    106 kDa

    基因ID

    290

    NCBI登录号

    NM_001150, NP_001141

    UniProt

    P15144

    途径

    Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
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