HIST1H2AE 抗体 (Middle Region)
Quick Overview for HIST1H2AE 抗体 (Middle Region) (ABIN2788645)
抗原
See all HIST1H2AE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- TAEILELAGN AARDNKKTRI IPRHLQLAIR NDEELNKLLG RVTIAQGGVL
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预测反应
- Cow: 100%, Human: 100%, Pig: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against HIST1H2AE. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 130 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HIST1H2AE (Histone Cluster 1, H2ae (HIST1H2AE))
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别名
- HIST1H2AE
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背景
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Alias Symbols: H2A.1, H2A.2, H2A/a, H2AFA, HIST1H2AB
Protein Interaction Partner: UBC, HUWE1, SUZ12, EZH2, ITGA4, CAND1, COPS5, CUL1, CUL4A, CUL4B, CUL5, NFX1, NEDD8, TONSL, SUMO1, EID1, UHRF1, NAP1L4,
Protein Size: 130 -
分子量
- 14 kDa
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基因ID
- 3012
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NCBI登录号
- NM_021052, NP_066390
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UniProt
- Q7L7L0
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途径
- Telomere Maintenance
抗原
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