Cathepsin K 抗体 (Middle Region)
Quick Overview for Cathepsin K 抗体 (Middle Region) (ABIN2788629)
抗原
See all Cathepsin K (CTSK) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- SPQNLVDCVS ENDGCGGGYM TNAFQYVQKN RGIDSEDAYP YVGQEESCMY
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预测反应
- Cow: 100%, Dog: 100%, Goat: 82%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against CTSK. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CTSK
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anti-Cathepsin K (CTSK) (AA 54-317) antibody
CTSK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin K (CTSK) (AA 163-274) antibodyCTSK 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CTSK-2791 unconjugated
anti-Cathepsin K (CTSK) (AA 220-329) antibodyCTSK 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Cathepsin K (CTSK) (AA 115-329) antibodyCTSK 适用: 人 WB 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Cathepsin K (CTSK) (AA 71-319) antibodyCTSK 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin K (CTSK) (AA 115-329) antibodyCTSK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin K (CTSK) (AA 220-331) antibodyCTSK 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Cathepsin K (CTSK) (AA 115-329) antibodyCTSK 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin K (CTSK) (N-Term) antibodyCTSK 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin K (CTSK) (AA 97-126) antibodyCTSK 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19253 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 329 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Cathepsin K (CTSK)
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别名
- CTSK
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背景
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The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
Alias Symbols: CTS02, CTSO, CTSO1, CTSO2, MGC23107, PKND, PYCD
Protein Interaction Partner: LIG4, SERPINB13, SERPINB3, KNG1, SPARC, FGFR3,
Protein Size: 329 -
分子量
- 37 kDa
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基因ID
- 1513
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NCBI登录号
- NM_000396, NP_000387
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UniProt
- P43235
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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