ST5 抗体 (Middle Region)
Quick Overview for ST5 抗体 (Middle Region) (ABIN2788427)
抗原
See all ST5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- VPKPKRTFEY EADKNPKSKP SNGLPPSPTP AAPPPLPSTP APPVTRRPKK
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against ST5. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ST5
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1137 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ST5 (Suppression of Tumorigenicity 5 (ST5))
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别名
- ST5
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背景
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This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.
Alias Symbols: DENND2B, HTS1, MGC33090, p126
Protein Interaction Partner: SMAD2, UBC, ABL1, SFN,
Protein Size: 1137 -
分子量
- 126 kDa
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基因ID
- 6764
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NCBI登录号
- NM_005418, NP_005409
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UniProt
- P78524
抗原
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