MAPKSP1 抗体 (N-Term)
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Quick Overview for MAPKSP1 抗体 (N-Term) (ABIN2788404)
抗原
See all MAPKSP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- LPSVEGLHAI VVSDRDGVPV IKVANDNAPE HALRPGFLST FALATDQGSK
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against LAMTOR3. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human LAMTOR3
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))
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别名
- LAMTOR3
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背景
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This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13.
Alias Symbols: MAP2K1IP1, MAPBP, MAPKSP1, MP1, PRO0633, Ragulator3
Protein Interaction Partner: NIF3L1, LAMTOR2, IBTK, MBD2, BHMT, PEF1, C19orf70, MRPL43, PRR3, LPCAT1, MRPS9, MRPS35, MRPL47, TOMM22, DDX28, TSR1, RNMTL1, LAMTOR1, NDUFB11, TMCO1, MRPL39, PTRH2, RAB14, MRPL51, MRPL22, UQCRQ, PUF60, RAB31, TOMM40, MSLN, TOMM70A, NUPL1, SPCS2, PICALM, V
Protein Size: 124 -
分子量
- 13 kDa
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基因ID
- 8649
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NCBI登录号
- NM_021970, NP_068805
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UniProt
- Q9UHA4
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途径
- PI3K-Akt Signaling
抗原
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