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AKR1C1 抗体 (N-Term)

This anti-AKR1C1 antibody (ABIN2788358) is a Rabbit Polyclonal antibody detecting AKR1C1 in WB, IHC. Suitable for Human, Rat, Cow, Dog, Horse, Rabbit, Pig.
产品编号 ABIN2788358
发货至: 中国

Quick Overview for AKR1C1 抗体 (N-Term) (ABIN2788358)

抗原

See all AKR1C1 (DDH) 抗体
AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

适用

  • 36
  • 10
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠, Cow, 犬, 马, 兔, Pig

宿主

  • 29
  • 7

克隆类型

  • 32
  • 4
多克隆

标记

  • 25
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This AKR1C1 antibody is un-conjugated

应用范围

  • 23
  • 12
  • 11
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    LERSLKNLQL DYVDLYLIHF PVSVKPGEEV IPKDENGKIL FDTVDLCATW

    预测反应

    Cow: 86%, Dog: 77%, Horse: 77%, Human: 100%, Pig: 77%, Rabbit: 82%, Rat: 82%

    产品特性

    This is a rabbit polyclonal antibody against AKR1C1. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human AKR1C1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 323 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

    别名

    AKR1C1

    背景

    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
    Alias Symbols: 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DDH, DDH1, H-37, HAKRC, MBAB, MGC8954, HBAB, DD1/DD2
    Protein Interaction Partner: PTPN3, UBC, FN1, COMMD8, MAPK3, AKR1C1,
    Protein Size: 323

    分子量

    36 kDa

    基因ID

    1645

    NCBI登录号

    NM_001353, NP_001344

    UniProt

    Q04828

    途径

    Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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