CTSC 抗体 (Middle Region)
Quick Overview for CTSC 抗体 (Middle Region) (ABIN2788336)
抗原
See all CTSC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- WTATTYMEYE TLTLGDMIRR SGGHSRKIPR PKPAPLTAEI QQKILHLPTS
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预测反应
- Cow: 86%, Dog: 79%, Horse: 86%, Human: 100%, Mouse: 79%
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产品特性
- This is a rabbit polyclonal antibody against CTSC. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CTSC
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anti-Cathepsin C (CTSC) (AA 25-134) antibody
CTSC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (AA 231-463) antibodyCTSC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (Cleaved-Arg394) antibodyCTSC 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (AA 25-134) antibodyCTSC 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (AA 238-252) antibodyVerified CTSC 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (Arg394), (cleaved) antibodyCTSC 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (AA 1-463) antibodyCTSC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (AA 1-463) antibodyCTSC 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (AA 185-234) antibodyCTSC 适用: 人, 小鼠, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin C (CTSC) (AA 231-462) antibodyCTSC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 463 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CTSC (Cathepsin C (CTSC))
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别名
- CTSC
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背景
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CTSC is a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in CTSC have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.
Alias Symbols: CPPI, DPP1, DPPI, HMS, JP, JPD, PALS, PLS, DPP-I
Protein Interaction Partner: SUMO1, UBC, NEDD8, ARMC9, ANKMY2, ARIH1, UBA2, ADSL, FBXO6, XRN2, CAPN1, CD81, CTSC, CTSL,
Protein Size: 463 -
分子量
- 8 kDa
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基因ID
- 1075
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NCBI登录号
- NM_001814, NP_001805
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UniProt
- P53634
抗原
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