Factor VIII 抗体 (C-Term)
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北京 101111
Quick Overview for Factor VIII 抗体 (C-Term) (ABIN2788318)
抗原
See all Factor VIII (F8) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- F8 Antibody - C-terminal region
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序列
- IMVTFRNQAS RPYSFYSSLI SYEEDQRQGA EPRKNFVKPN ETKTYFWKVQ
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预测反应
- Cow: 86%, Dog: 77%, Horse: 93%, Human: 100%, Rabbit: 86%, Sheep: 86%
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产品特性
- This is a rabbit polyclonal antibody against F8. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human F8
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anti-Coagulation Factor VIII (F8) (AA 2253-2346) antibody
F8 适用: 人 IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 1887-2044) antibodyF8 适用: 人 IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 1854-1988) antibodyF8 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 1451-1550) antibodyF8 适用: 人 IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (Middle Region) antibodyF8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 401-500) antibodyF8 适用: 大鼠 IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 85-190) antibodyF8 适用: 人 IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 213-312) antibodyF8 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 1E8 unconjugated
anti-Coagulation Factor VIII (F8) (AA 1-216) antibodyF8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 1669-1824) antibodyF8 适用: Pig WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60040-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Factor VIII (F8) (Coagulation Factor VIII (F8))
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别名
- F8
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背景
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Background Information: This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
Gene Name: Coagulation factor VIII, procoagulant component
Alternative Symbols: AHF, F8B, F8C, HEMA, FVIII, DXS1253E
Protein Name: Coagulation factor VIII
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分子量
- 79kDa
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基因ID
- 2157
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NCBI登录号
- NP_000123
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UniProt
- P00451
抗原
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