ADRA2C 抗体 (C-Term)
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Quick Overview for ADRA2C 抗体 (C-Term) (ABIN2788285)
抗原
See all ADRA2C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- RAGAEGGAGG ADGQGAGPGA AESGALTASR EWGGERGRPL CLPPSARGCF
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预测反应
- Human: 100%, Pig: 85%
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产品特性
- This is a rabbit polyclonal antibody against ADRA2C. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of human ADRA2C
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))
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别名
- ADRA2C
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背景
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Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.
Alias Symbols: ADRA2L2, ADRARL2, ADRA2RL2, ALPHA2CAR
Protein Size: 374 -
分子量
- 41 kDa
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基因ID
- 152
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NCBI登录号
- NM_000683, NP_000674
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UniProt
- P18825
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途径
- EGFR Signaling Pathway, cAMP Metabolic Process
抗原
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