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ADRA2C 抗体 (C-Term)

This anti-ADRA2C antibody is a 兔 多克隆 antibody detecting ADRA2C in WB. Suitable for 人 和 Pig.
产品编号 ABIN2788285
发货至: 中国

Quick Overview for ADRA2C 抗体 (C-Term) (ABIN2788285)

抗原

See all ADRA2C 抗体
ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

适用

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人, Pig

宿主

  • 56
  • 30

克隆类型

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  • 30
多克隆

标记

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  • 1
  • 1
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This ADRA2C antibody is un-conjugated

应用范围

  • 56
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  • 11
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Western Blotting (WB)
  • 抗原表位

    • 22
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    C-Term

    序列

    RAGAEGGAGG ADGQGAGPGA AESGALTASR EWGGERGRPL CLPPSARGCF

    预测反应

    Human: 100%, Pig: 85%

    产品特性

    This is a rabbit polyclonal antibody against ADRA2C. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of human ADRA2C
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

    别名

    ADRA2C

    背景

    Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.
    Alias Symbols: ADRA2L2, ADRARL2, ADRA2RL2, ALPHA2CAR
    Protein Size: 374

    分子量

    41 kDa

    基因ID

    152

    NCBI登录号

    NM_000683, NP_000674

    UniProt

    P18825

    途径

    EGFR Signaling Pathway, cAMP Metabolic Process
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