BBS10 抗体 (C-Term)
Quick Overview for BBS10 抗体 (C-Term) (ABIN2788220)
抗原
See all BBS10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- SQTGLESVMG KYQLLTSVLQ CLTKILTIDM VITVKRHPQK VHNQDSEDEL
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预测反应
- Human: 100%, Rabbit: 86%
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产品特性
- This is a rabbit polyclonal antibody against BBS10. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human BBS10
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anti-Bardet-Biedl Syndrome 10 (BBS10) (Internal Region) antibody
BBS10 适用: 人, 小鼠, 斑马鱼 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 10 (BBS10) antibodyBBS10 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 10 (BBS10) (AA 474-723) antibodyBBS10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 10 (BBS10) (AA 515-544), (C-Term) antibodyBBS10 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB24715 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 723 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- BBS10 (Bardet-Biedl Syndrome 10 (BBS10))
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别名
- BBS10
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背景
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This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes. Mutations in this gene cause Bardet-Biedl syndrome type 10.
Alias Symbols: C12orf58, FLJ23560
Protein Interaction Partner: UBC, YAE1D1, MAPK8IP2, HDAC6, TNFSF11, MAP3K7, RGS2, RASA1, PTK2, MAPK6, NR4A1, FRZB, CSNK1E,
Protein Size: 723 -
分子量
- 81 kDa
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基因ID
- 79738
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NCBI登录号
- NM_024685, NP_078961
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UniProt
- Q8TAM1
抗原
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