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CRY1 抗体 (N-Term)

This anti-CRY1 antibody is a 兔 多克隆 antibody detecting CRY1 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 绵羊 和 斑马鱼. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2788200
发货至: 中国

Quick Overview for CRY1 抗体 (N-Term) (ABIN2788200)

抗原

See all CRY1 抗体
CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))

适用

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人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 绵羊, 斑马鱼

宿主

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  • 7
  • 1

克隆类型

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多克隆

标记

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This CRY1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    KRFQTLISKM EPLEIPVETI TSEVIEKCTT PLSDDHDEKY GVPSLEELGF

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against CRY1. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human CRY1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 586 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Currie, Doherty, Sillar: "Deep-brain photoreception links luminance detection to motor output in Xenopus frog tadpoles." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 21, pp. 6053-8, (2016) (PubMed).

  • 抗原

    CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))

    别名

    CRY1

    背景

    CRY1 is the blue light-dependent regulator of the circadian feedback loop. CRY1 inhibits CLOCK NPAS2-ARNTL E box-mediated transcription. CRY1 acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. CRY1 has no photolyase activity. CRY1 is capable of translocating circadian clock core proteins such as PER proteins to the nucleus. CRY1 may inhibit CLOCK NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL.
    Alias Symbols: PHLL1
    Protein Interaction Partner: PER2, FBXL3, FBXL21, PLSCR1, BTRC, CUL1, SKP1, CSNK1E, LTBP4, UBC, SNRPD3, GRN, USP2, Timeless, Cry1, KRTAP4-12, PER3, MDFI, CBLB, ARNTL, PER1, TRAF2,
    Protein Size: 586

    分子量

    64 kDa

    基因ID

    1407

    NCBI登录号

    NM_004075, NP_004066

    UniProt

    Q16526

    途径

    Response to Water Deprivation, Proton Transport
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