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RASSF1 抗体 (C-Term)

This anti-RASSF1 antibody is a 兔 多克隆 antibody detecting RASSF1 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 绵羊, 斑马鱼, 豚鼠 和 兔.
产品编号 ABIN2788160
发货至: 中国

Quick Overview for RASSF1 抗体 (C-Term) (ABIN2788160)

抗原

See all RASSF1 抗体
RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

适用

人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 绵羊, 斑马鱼, 豚鼠, 兔

宿主

  • 46
  • 11
  • 1

克隆类型

  • 47
  • 11
多克隆

标记

  • 29
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RASSF1 antibody is un-conjugated

应用范围

  • 29
  • 23
  • 13
  • 13
  • 11
  • 6
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    C-Term

    序列

    LAGPSDKALS FVLKENDSGE VNWDAFSMPE LHNFLRILQR EEEEHLRQIL

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 85%

    产品特性

    This is a rabbit polyclonal antibody against RASSF1. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human RASSF1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 270 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

    别名

    RASSF1

    背景

    This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
    Alias Symbols: 123F2, NORE2A, RASSF1A, RDA32, REH3P21
    Protein Interaction Partner: FBXW11, MDM2, DAXX, SUV39H2, KDM1A, SUV39H1, STK4, STK3, CDC20, SAV1, MAST2, HUWE1, LATS1, BTRC, UBC, ID1, GSK3B, C7orf25, C8orf33, KCNE3, CUL4A, DDB1, Rassf1, SKP2, AURKB, AURKA, SKP1, CUL1, NUDT10, MOAP1, CNKSR1, MAP1S, EXOSC8, RASSF5, TNFRSF10A, E4F1,
    Protein Size: 270

    分子量

    30 kDa

    基因ID

    11186

    NCBI登录号

    NM_170713, NP_733831

    UniProt

    Q9NS23
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