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RASSF5 抗体 (C-Term)

RASSF5 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2788157
发货至: 中国
  • 抗原 See all RASSF5 抗体
    RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))
    抗原表位
    • 15
    • 3
    • 2
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔
    宿主
    • 20
    • 5
    克隆类型
    • 23
    • 2
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RASSF5 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 10
    • 7
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    SFVLKENETG EVEWDAFSIP ELQNFLTILE KEEQDKIHQL QKKYNKFRQK
    预测反应
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 92%
    产品特性
    This is a rabbit polyclonal antibody against Rassf5. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Rassf5
    Top Product
    Discover our top product RASSF5 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))
    别名
    Rassf5 (RASSF5 产品)
    别名
    Maxp1 antibody, NORE1 antibody, NORE1A antibody, NORE1B antibody, RAPL antibody, RASSF3 antibody, 1300019G20Rik antibody, AU042887 antibody, Nore1 antibody, Nore1A antibody, Nore1B antibody, Rapl antibody, Ras association domain family member 5 antibody, Ras association (RalGDS/AF-6) domain family member 5 antibody, RASSF5 antibody, Rassf5 antibody
    背景
    Rassf5 is a potental tumor suppressor. It seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. It may be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS1 and KRAS induced apoptosis.
    Alias Symbols: 1300019G20Rik, AU042887, Maxp1, Nore1, Nore1A, Nore1B, Rapl
    Protein Interaction Partner: Hras,
    Protein Size: 413
    分子量
    47 kDa
    基因ID
    54354
    NCBI登录号
    NM_018750, NP_061220
    UniProt
    Q5EBH1
    途径
    TCR Signaling
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