RASSF5 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for RASSF5 抗体 (C-Term) (ABIN2788157)
抗原
See all RASSF5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
序列
- SFVLKENETG EVEWDAFSIP ELQNFLTILE KEEQDKIHQL QKKYNKFRQK
-
预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 92%
-
产品特性
- This is a rabbit polyclonal antibody against Rassf5. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Rassf5
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeat freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))
-
别名
- Rassf5
-
背景
-
Rassf5 is a potental tumor suppressor. It seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. It may be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS1 and KRAS induced apoptosis.
Alias Symbols: 1300019G20Rik, AU042887, Maxp1, Nore1, Nore1A, Nore1B, Rapl
Protein Interaction Partner: Hras,
Protein Size: 413 -
分子量
- 47 kDa
-
基因ID
- 54354
-
NCBI登录号
- NM_018750, NP_061220
-
UniProt
- Q5EBH1
-
途径
- TCR Signaling
抗原
-