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GPR172A 抗体 (C-Term)

The 兔 多克隆 anti-GPR172A antibody (ABIN2788146) specifically detects GPR172A in WB. The antibody is reactive with 人, 小鼠, 大鼠, Pig, 马, 豚鼠, 犬 和 Cow samples.
产品编号 ABIN2788146
发货至: 中国
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Quick Overview for GPR172A 抗体 (C-Term) (ABIN2788146)

抗原

See all GPR172A 抗体
GPR172A (G Protein-Coupled Receptor 172A (GPR172A))

适用

人, 小鼠, 大鼠, Pig, 马, 豚鼠, 犬, Cow

宿主

  • 30
兔

克隆类型

  • 30
多克隆

标记

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This GPR172A antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    原理

    SLC52A2 Antibody - C-terminal region

    序列

    SLPSVTTGGS GPELQLGSPG AEEEEKEEEE ALPLQEPPSQ AAGTIPGPDP

    预测反应

    Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 93%, Rat: 85%

    产品特性

    This is a rabbit polyclonal antibody against SLC52A1. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of human SLC52A2
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59638-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    GPR172A (G Protein-Coupled Receptor 172A (GPR172A))

    别名

    SLC52A2

    背景

    Background Information: This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia.

    Gene Name: solute carrier family 52 (riboflavin transporter), member 2

    Alternative Symbols: PAR1, RFT3, RFVT2, hRFT3, BVVLS2, GPCR41, GPR172A, D15Ertd747e

    Protein Name: solute carrier family 52, riboflavin transporter, member 2

    分子量

    38kDa

    基因ID

    79581

    NCBI登录号

    NP_001240744

    UniProt

    Q9HAB3

    途径

    Nuclear Receptor Transcription Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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