GPR172A 抗体 (C-Term)
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北京 101111
Quick Overview for GPR172A 抗体 (C-Term) (ABIN2788146)
抗原
See all GPR172A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- SLC52A2 Antibody - C-terminal region
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序列
- SLPSVTTGGS GPELQLGSPG AEEEEKEEEE ALPLQEPPSQ AAGTIPGPDP
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预测反应
- Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 93%, Rat: 85%
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产品特性
- This is a rabbit polyclonal antibody against SLC52A1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of human SLC52A2
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59638-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- GPR172A (G Protein-Coupled Receptor 172A (GPR172A))
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别名
- SLC52A2
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背景
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Background Information: This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia.
Gene Name: solute carrier family 52 (riboflavin transporter), member 2
Alternative Symbols: PAR1, RFT3, RFVT2, hRFT3, BVVLS2, GPCR41, GPR172A, D15Ertd747e
Protein Name: solute carrier family 52, riboflavin transporter, member 2
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分子量
- 38kDa
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基因ID
- 79581
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NCBI登录号
- NP_001240744
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UniProt
- Q9HAB3
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途径
- Nuclear Receptor Transcription Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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