HNMT 抗体 (N-Term)
-
- 抗原 See all HNMT 抗体
- HNMT (Histamine N-Methyltransferase (HNMT))
-
抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, Pig, 兔
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This HNMT antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- PGIIGRIGDT KSEIKILSIG GGAGEIDLQI LSKVQAQYPG VCINNEVVEP
- 预测反应
- Cow: 92%, Dog: 92%, Guinea Pig: 77%, Horse: 92%, Human: 100%, Mouse: 77%, Pig: 92%, Rabbit: 92%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against HNMT. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HNMT
- Top Product
- Discover our top product HNMT Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 292 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- HNMT (Histamine N-Methyltransferase (HNMT))
- 别名
- HNMT (HNMT 产品)
- 背景
-
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
Alias Symbols: HMT, HNMT-S1, HNMT-S2
Protein Interaction Partner: CAMK2D, DSP, TINF2, POT1, TERF1,
Protein Size: 292 - 分子量
- 33 kDa
- 基因ID
- 3176
- NCBI登录号
- NM_006895, NP_008826
- UniProt
- P50135
-