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GRM7 抗体 (C-Term)

This anti-GRM7 antibody is a 兔 多克隆 antibody detecting GRM7 in WB. Suitable for 人, 大鼠, 小鼠, 犬, Cow, 兔, 马, 斑马鱼 和 豚鼠.
产品编号 ABIN2788134
发货至: 中国

Quick Overview for GRM7 抗体 (C-Term) (ABIN2788134)

抗原

See all GRM7 抗体
GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

适用

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人, 大鼠, 小鼠, 犬, Cow, 兔, 马, 斑马鱼, 豚鼠

宿主

  • 35
  • 11
  • 1

克隆类型

  • 36
  • 11
多克隆

标记

  • 35
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This GRM7 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    HPELNVQKRK RSFKAVVTAA TMSSRLSHKP SDRPNGEAKT ELCENVDPNS

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against GRM7. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human GRM7
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 915 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

    别名

    GRM7

    背景

    L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: FLJ40498, GLUR7, GPRC1G, MGLU7, MGLUR7
    Protein Interaction Partner: UBC, PICK1, TUBA8, TUBA1B, TUBA1A, TUBA3C, GNAQ, GRIPAP1, FLNA, TUBA4A, CALM3, CALM1, PRKCA, GRIP1, SDCBP,
    Protein Size: 915

    分子量

    99 kDa

    基因ID

    2917

    NCBI登录号

    NM_000844, NP_000835

    UniProt

    Q14831

    途径

    Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour
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