COCH 抗体 (C-Term)
Quick Overview for COCH 抗体 (C-Term) (ABIN2788126)
抗原
See all COCH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- VAWAPLDDLK DMASKPKESH AFFTREFTGL EPIVSDVIRG ICRDFLESQQ
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against COCH. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human COCH
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anti-Cochlin (COCH) (AA 20-260) antibody
COCH 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cochlin (COCH) antibodyCOCH 适用: 人 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cochlin (COCH) (AA 1-494) antibodyCOCH 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cochlin (COCH) (AA 141-190) antibodyCOCH 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Cochlin (COCH) (AA 20-260) antibodyCOCH 适用: 人 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cochlin (COCH) (AA 399-428) antibodyCOCH 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21184 unconjugated
anti-Cochlin (COCH) (AA 398-428), (Middle Region) antibodyCOCH 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Cochlin (COCH) (AA 20-260) antibodyCOCH 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cochlin (COCH) (C-Term) antibodyCOCH 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, 斑马鱼, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Cochlin (COCH) (N-Term) antibodyCOCH 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 550 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- COCH (Cochlin (COCH))
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别名
- COCH
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背景
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The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94 % and 79 % amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated.
Alias Symbols: COCH-5B2, COCH5B2, DFNA9
Protein Interaction Partner: FBXO6,
Protein Size: 550 -
分子量
- 57 kDa
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基因ID
- 1690
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NCBI登录号
- NM_001135058, NP_001128530
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UniProt
- O43405
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途径
- Sensory Perception of Sound
抗原
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