AVPR2 抗体 (C-Term)
Quick Overview for AVPR2 抗体 (C-Term) (ABIN2788110)
抗原
See all AVPR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- NPWIYASFSS SVSSELRSLL CCARGRTPPS LGPQDESCTT ASSSLAKDTS
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预测反应
- Cow: 79%, Dog: 79%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Sheep: 79%
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产品特性
- This is a rabbit polyclonal antibody against AVPR2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human AVPR2
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anti-Arginine Vasopressin Receptor 2 (AVPR2) (C-Term) antibody
AVPR2 适用: 人, 猴, Cow, 犬, 豚鼠, 绵羊 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 2 (AVPR2) (AA 221-271) antibodyAVPR2 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 2 (AVPR2) (AA 343-377), (C-Term) antibodyAVPR2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB52186 unconjugated
anti-Arginine Vasopressin Receptor 2 (AVPR2) (C-Term) antibodyAVPR2 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 2 (AVPR2) (Cytoplasmic Domain) antibodyAVPR2 适用: 人, 小鼠, 大鼠, 猴, 兔, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 2 (AVPR2) (Internal Region) antibodyAVPR2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 2 (AVPR2) antibodyAVPR2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 2 (AVPR2) (AA 65-170) antibodyAVPR2 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 2 (AVPR2) (AA 1-50) antibodyAVPR2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 371 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- AVPR2 (Arginine Vasopressin Receptor 2 (AVPR2))
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别名
- AVPR2
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背景
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This gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non-mammals, is well conserved, though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost, the disease Nephrogenic Diabetes Insipidus (NDI) results. The V2 receptor is also expressed outside the kidney although its tissue localization is uncertain. When these 'extrarenal receptors' are stimulated by infusion of a V2 selective agonist (dDAVP), a variety of clotting factors are released into the bloodstream. The physiologic importance of this property is not known - its absence does not appear to be detrimental in NDI patients. The gene expression has also been described in fetal lung tissue and lung cancer associated with alternative splicing.
Alias Symbols: ADHR, DI1, DIR, DIR3, MGC126533, MGC138386, NDI, V2R
Protein Interaction Partner: ARRDC4, ARRDC3, GNG2, GNB1, GNAS, STUB1, UBC, DERL1, VCP, C1QTNF1, GRK5, AVP, ARRB2, MAPK3, PRKCA,
Protein Size: 371 -
分子量
- 40 kDa
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基因ID
- 554
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NCBI登录号
- NM_000054, NP_000045
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UniProt
- P30518
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途径
- cAMP Metabolic Process
抗原
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