NUMB 抗体 (C-Term)
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- 抗原 See all NUMB 抗体
- NUMB (Numb Homolog (NUMB))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠, Cow, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NUMB antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- ASGNRHAEVP PGTCPVDPFE AQWAALESKS KQRTNPSPTN PFSSDLQKTF
- 预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against Numb. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product NUMB Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 604 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- NUMB (Numb Homolog (NUMB))
- 别名
- Numb (NUMB 产品)
- 别名
- C14orf41 antibody, S171 antibody, c14_5527 antibody, Nb antibody, NUMB, endocytic adaptor protein antibody, numb homolog (Drosophila) antibody, NUMB antibody, Numb antibody, numb antibody
- 背景
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Numb plays a role in the process of neurogenesis. It is required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. It is not required for the proliferation of neural progenitor cells before the onset of neurogenesis. It is also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. It may also mediate local repair of brain ventricular wall damage.
Alias Symbols: m-numb, mnb, m-Nb
Protein Interaction Partner: Igsf5, Eed, Grin1, Cdh2, Cdh1, Ctnnb1, Ctnna1, Lnx2, Lnx1, Notch1, Eps15, Ehd1, Ehd4,
Protein Size: 604 - 分子量
- 66 kDa
- 基因ID
- 18222
- NCBI登录号
- NM_010949, NP_035079
- 途径
- Cell-Cell Junction Organization
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