COPS6 抗体 (Middle Region)
(1 reference)Quick Overview for COPS6 抗体 (Middle Region) (ABIN2788037)
抗原
See all COPS6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- DHVARMTATG SGENSTVAEH LIAQHSAIKM LHSRVKLILE YVKASEAGEV
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
-
产品特性
- This is a rabbit polyclonal antibody against COPS6. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human COPS6
-
-
anti-COP9 Signalosome Complex Subunit 6 (COPS6) (AA 58-327) antibody
COPS6 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 4E7 unconjugated
anti-COP9 Signalosome Complex Subunit 6 (COPS6) (AA 58-327) antibodyCOPS6 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2F5 unconjugated
anti-COP9 Signalosome Complex Subunit 6 (COPS6) (AA 58-327) antibodyCOPS6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 6 (COPS6) antibodyCOPS6 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 6 (COPS6) (AA 201-250) antibodyCOPS6 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 6 (COPS6) (AA 1-327) antibodyCOPS6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 6 (COPS6) (AA 30-327) antibodyCOPS6 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2H5 unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 327 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
-
: "The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain." in: PLoS ONE, Vol. 7, Issue 8, pp. e43980, (2012) (PubMed).
-
: "The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain." in: PLoS ONE, Vol. 7, Issue 8, pp. e43980, (2012) (PubMed).
-
- COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))
-
别名
- COPS6
-
背景
-
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
Alias Symbols: CSN6, MOV34-34KD
Protein Interaction Partner: NEDD8, CUL1, UBC, COPS5, GPS1, SUMO1, POP7, COPS7B, COPS7A, CUL4B, USP7, COPS4, FBXO6, FBXW4, IGHV3OR15-7, vpr, TP63, RFWD2, SFN, IRF5, COPS8, COPS2, COPS3, DDB2, DDB1, ERCC8, TOR1AIP2, LRR1, RBX1, VPRBP, LRRC14, CUL2, CUL3, CUL4A, CUL5, TCEB2, TCEB1, SKP
Protein Size: 327 -
分子量
- 36 kDa
-
基因ID
- 10980
-
NCBI登录号
- NM_006833, NP_006824
-
UniProt
- Q7L5N1
-
途径
- Cell Division Cycle
抗原
-
