USP6 抗体 (C-Term)
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北京 101111
Quick Overview for USP6 抗体 (C-Term) (ABIN2501038)
抗原
See all USP6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- NHSEEDSTDD QREDTHIKPI YNLYAISCHS GILSGGHYIT YAKNPNCKWY
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 91%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against USP6. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human USP6
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- USP6 (Ubiquitin Specific Peptidase 6 (USP6))
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别名
- USP6
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背景
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USP6 is a deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. It catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. USP6 promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. It is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.
Protein Interaction Partner: EXOSC8, CALM2, MDFI, APP, ATXN7L3, ANKRD44, RAB33B, MYL2, ARF6, RAC1, CDC42, UBC, USP32,
Protein Size: 1089 -
分子量
- 119 kDa
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基因ID
- 9098
抗原
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