USP10 抗体 (C-Term)
Quick Overview for USP10 抗体 (C-Term) (ABIN2788016)
抗原
See all USP10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- RDIRPGAAFE PTYIYRLLTV IKSSLSEKGR QEDAEEYLGF ILNGLHEEML
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against Usp10. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-Ubiquitin Specific Peptidase 10 (USP10) antibody
USP10 适用: 人, 小鼠, 大鼠, 猴, 犬 WB, IF, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 2E1 unconjugated
anti-Ubiquitin Specific Peptidase 10 (USP10) antibodyUSP10 适用: 人, 猴 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 1H9 unconjugated
anti-Ubiquitin Specific Peptidase 10 (USP10) antibodyUSP10 适用: 人 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 1A10 unconjugated
anti-Ubiquitin Specific Peptidase 10 (USP10) (AA 1-798) antibodyUSP10 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 10 (USP10) (AA 699-797) antibodyUSP10 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B8 unconjugated
anti-Ubiquitin Specific Peptidase 10 (USP10) (AA 1-798) antibodyUSP10 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 10 (USP10) antibodyUSP10 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Ubiquitin Specific Peptidase 10 (USP10) (N-Term) antibodyUSP10 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 10 (USP10) (AA 487-536) antibodyUSP10 适用: 人, 小鼠, 大鼠, 猴, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 10 (USP10) (AA 301-350) antibodyUSP10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 794 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- USP10 (Ubiquitin Specific Peptidase 10 (USP10))
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别名
- Usp10
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背景
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Usp10 is a hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. It acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53. Following DNA damage, translocates to the nucleus and deubiquitinates p53/TP53, leading to regulate the p53/TP53-dependent DNA damage response. Usp10 does not deubiquitinate MDM2 and deubiquitinates CFTR in early endosomes, enhancing its endocytic recycling.
Alias Symbols: MGC124997
Protein Size: 794 -
分子量
- 87 kDa
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基因ID
- 307905
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NCBI登录号
- NM_001034146, NP_001029318
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UniProt
- Q3KR59
抗原
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