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USP7 抗体 (Middle Region)

Name: USP7 抗体 (Middle Region)
SKU: ABIN2787924
Availability: OutOfStock

This anti-USP7 antibody is a 兔多克隆 antibody detecting USP7 in WB. Suitable for 人, 小鼠, 大鼠, 犬, 马, Cow, 兔, 斑马鱼和豚鼠. This Primary Antibody has been cited in 1 publication.

Host: Rat Target Name: USP7 Sample Tissue: Rat Brain Antibody Dilution: 1ug/ml (USP7 抗体 (Middle Region))

WB Suggested Anti-USP7 Antibody Titration: 0. (USP7 抗体 (Middle Region))

2 images

(1 reference)

产品编号 ABIN2787924

发货至: 中国

Quick Overview for USP7 抗体 (Middle Region) (ABIN2787924)

抗原

See all USP7 抗体

USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))

适用

人, 小鼠, 大鼠, 犬, 马, Cow, 兔, 斑马鱼, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This USP7 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product USP7 Primary Antibody

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Middle Region

序列

RVLLDNVENK MKGTCVEGTI PKLFRGKMVS YIQCKEVDYR SDRREDYYDI

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

产品特性

This is a rabbit polyclonal antibody against USP7. It was validated on Western Blot.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human USP7
anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) (AA 54-507) antibody
USP7 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) antibody
USP7 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 7F10 unconjugated Recombinant Antibody

anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) (AA 206-1102) antibody
USP7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) (AA 1050-1100) antibody
USP7 适用: 人, 小鼠, 大鼠, 犬, 马, 小鸡, Macaque WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) (Internal Region) antibody
USP7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) (AA 258-483) antibody
USP7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) (AA 302-394), (C-Term) antibody
USP7 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) (AA 30-80) antibody
USP7 适用: 人, 小鼠, 大鼠, 犬, 马, 小鸡, Macaque WB 宿主: 兔 Polyclonal unconjugated

anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) antibody
USP7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5F11 unconjugated

anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) (AA 1060-1090), (C-Term) antibody
USP7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4281 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 1102 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Nie, Zhang, Dai, Zhang, Zhao, Xu, Chen, Wang, Wang, Qiao: "Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation." in: Biology of reproduction, Vol. 94, Issue 2, pp. 31, (2016) (PubMed).
抗原

USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))

别名

USP7

背景

USP7 is a hydrolase that deubiquitinates target proteins such as FOXO4, TP53, MDM2, PTEN and DAXX. Together with DAXX, USP7 prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards TP53, thereby promoting TP53 ubiquitination and proteasomal degradation. USP7 deubiquitinates TP53 and MDM2 and strongly stabilizes TP53 even in the presence of excess MDM2, and also induces TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, USP7 is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. USP7 is involved in cell proliferation during early embryonic development. USP7 contributes to the overall stabilization and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection.
Alias Symbols: HAUSP, TEF1
Protein Interaction Partner: UBC, TP53, CHFR, RNF220, TPP1, FAM175B, HUWE1, PEPD, XPC, SUMO2, IKBKG, SHFM1, RB1, SUMO1, RPA3, RPA2, RPA1, PTEN, EED, ABL1, RNF2, MMS19, PPP6C, FKBP5, PPP6R3, CDC37, OGFR, COPS6, MAGED2, TRAP1, MCMBP, CLK3, UHRF1, PPARG, RNF11, KAT5, SOX2, LOC576779, HD
Protein Size: 1102

分子量

128 kDa

基因ID

7874

NCBI登录号

NM_003470, NP_003461

UniProt

Q93009