TXNIP 抗体 (N-Term)
Quick Overview for TXNIP 抗体 (N-Term) (ABIN2787923)
抗原
See all TXNIP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- QTSEYLRYED TLLLEDQPTG ENEMVIMRPG NKYEYKFGFE LPQGPLGTSF
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预测反应
- Cow: 79%, Dog: 100%, Guinea Pig: 87%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against TXNIP. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human TXNIP
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anti-Thioredoxin Interacting Protein (TXNIP) (AA 30-381) antibody
TXNIP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 1-166) antibodyTXNIP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 32-367) antibodyTXNIP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibodyTXNIP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 1-30), (N-Term) antibodyTXNIP 适用: 人 WB 宿主: 兔 Polyclonal RB41554 unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 116-145) antibodyTXNIP 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB30652 unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (Internal Region) antibodyTXNIP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 101-200) antibodyTXNIP 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibodyTXNIP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 绵羊, 猴, Bat, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 299-381) antibodyTXNIP 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TXNIP (Thioredoxin Interacting Protein (TXNIP))
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别名
- TXNIP
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背景
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TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells.
Protein Interaction Partner: UBC, DDIT4, ECD, TXN, TP53, SMURF2, UL49, ITCH, ELAVL1, FHL1, ZBTB32, ZBTB16, SCEL, HDAC1, TXNRD1, KPNA2,
Protein Size: 391 -
分子量
- 43 kDa
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基因ID
- 10628
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NCBI登录号
- XP_003960219
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UniProt
- Q9H3M7
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途径
- Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
抗原
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