Calreticulin 抗体 (Middle Region)
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北京 101111
Quick Overview for Calreticulin 抗体 (Middle Region) (ABIN2787864)
抗原
See all Calreticulin (CALR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- ASKPEDWDER AKIDDPTDSK PEDWDKPEHI PDPDAKKPED WDEEMDGEWE
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against CALR. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CALR
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anti-Calreticulin (CALR) (AA 196-310) antibody
CALR 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Calreticulin (CALR) (AA 18-193) antibodyCALR 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Calreticulin (CALR) (AA 18-417) antibodyCALR 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7B3D7 unconjugated
anti-Calreticulin (CALR) antibodyCALR 适用: 人, 小鼠 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 1G6A7 unconjugated
anti-Calreticulin (CALR) (N-Term) antibodyCALR 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calreticulin (CALR) (AA 1-417) antibodyCALR 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G11-1A9 unconjugated
anti-Calreticulin (CALR) antibodyCALR 适用: 人 WB, IHC, IP, ICC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Calreticulin (CALR) (AA 277-305) antibodyCALR 适用: 人, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21112 unconjugated
anti-Calreticulin (CALR) antibody (HRP)CALR 适用: 人 WB, IHC, IP, ICC, FACS, IF 宿主: 兔 Polyclonal HRP
anti-Calreticulin (CALR) antibody (FITC)CALR 适用: 人 WB, IHC, IP, ICC, FACS, IF 宿主: 兔 Polyclonal FITC
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 417 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Calreticulin (CALR)
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别名
- CALR
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背景
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Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.
Alias Symbols: CRT, FLJ26680, RO, SSA, cC1qR
Protein Interaction Partner: HUWE1, UBC, LGR4, MDM2, RNF2, SUZ12, rev, AARSD1, THG1L, NSUN2, SH3GLB1, EEF2K, ARPC1A, ANP32B, ACTR2, ARPC1B, ARPC3, ARPC5, TPD52L2, SH3GL1, RPA3, RPA1, PRKACA, PFDN5, LPP, PARK2, UPF2, UBD, SOX2, PDIA3, CLN5, ITGA3, HLA-E, HLA-A, CALR, SLC27A2, env, MTN
Protein Size: 417 -
分子量
- 46 kDa
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基因ID
- 811
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NCBI登录号
- NM_004343, NP_004334
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UniProt
- P27797
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途径
- Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response
抗原
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