GARS 抗体 (Middle Region)
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- 抗原 See all GARS 抗体
- GARS (Glycyl-tRNA Synthetase (GARS))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, 斑马鱼, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GARS antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- IEPSFGLGRI MYTVFEHTFH VREGDEQRTF FSFPAVVAPF KCSVLPLSQN
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- 产品特性
- This is a rabbit polyclonal antibody against GARS. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human GARS
- Top Product
- Discover our top product GARS Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 739 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- GARS (Glycyl-tRNA Synthetase (GARS))
- 别名
- GARS (GARS 产品)
- 背景
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GARS catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs.This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMT2D, DSMAV, GlyRS, HMN5, SMAD1
Protein Interaction Partner: UBC, STAU1, NEDD8, DCP2, TNRC6B, CAND1, GORASP2, CORO1C, BOP1, GANAB, XPO7, HSPA4L, VAT1, SEC23A, TOM1, KHSRP, HIRIP3, HIST1H4A, USP11, ZYX, UGDH, TTC1, TROVE2, SNX1, SHMT1, PPM1G, OSBP, NCBP1, ME1, GTF2A1, GFPT1, CTTN, CTNNA1, CARS, APEH, MAPK8, MAP3K10,
Protein Size: 739 - 分子量
- 83 kDa
- 基因ID
- 2617
- NCBI登录号
- NM_002047, NP_002038
- UniProt
- P41250
- 途径
- Ribonucleoside Biosynthetic Process
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