ALDH1A1 抗体 (Middle Region)
Quick Overview for ALDH1A1 抗体 (Middle Region) (ABIN2787809)
抗原
See all ALDH1A1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- SVERAKKYIL GNPLTPGVTQ GPQIDKEQYD KILDLIESGK KEGAKLECGG
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 93%, Sheep: 93%, Yeast: 77%
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产品特性
- This is a rabbit polyclonal antibody against ALDH1A1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ALDH1A1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 501 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))
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别名
- ALDH1A1
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背景
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This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a cytosolic isoform, which has a high affinity for aldehydes.
Alias Symbols: ALDC, ALDH-E1, ALDH1, ALDH11, MGC2318, PUMB1, RALDH1
Protein Interaction Partner: ALDH1A1, SUMO1, NEDD8, NUPR1, POT1, NOS2, ALDH2, UBC,
Protein Size: 501 -
分子量
- 55 kDa
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基因ID
- 216
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NCBI登录号
- NM_000689, NP_000680
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UniProt
- P00352
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途径
- Dopaminergic Neurogenesis
抗原
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