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- 抗原 See all WDR77 抗体
- WDR77 (WD Repeat Domain 77 (WDR77))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WDR77 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MRKETPPPLV PPAAREWNLP PNAPACMERQ LEAARYRSDG ALLLGASSLS
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against WDR77. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human WDR77
- Top Product
- Discover our top product WDR77 Primary Antibody
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anti-WD Repeat Domain 77 (WDR77) (AA 1-342) antibody
WDR77 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 3F10 unconjugated
anti-WD Repeat Domain 77 (WDR77) (AA 1-260) antibodyWDR77 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 77 (WDR77) antibodyWDR77 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 77 (WDR77) (AA 1-260) antibodyWDR77 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 77 (WDR77) antibodyWDR77 适用: 人, 小鼠 WB, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-WD Repeat Domain 77 (WDR77) (AA 1-343) antibodyWDR77 适用: 人 ELISA, WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3F10 unconjugated
anti-WD Repeat Domain 77 (WDR77) (AA 1-312) antibodyWDR77 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 77 (WDR77) antibodyWDR77 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 77 (WDR77) (C-Term) antibodyWDR77 适用: 人, Orang-Utan ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 77 (WDR77) (AA 1-342) antibodyWDR77 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 342 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- WDR77 (WD Repeat Domain 77 (WDR77))
- 别名
- WDR77 (WDR77 产品)
- 别名
- MEP-50 antibody, MEP50 antibody, Nbla10071 antibody, RP11-552M11.3 antibody, p44 antibody, p44/Mep50 antibody, 2610003I18Rik antibody, 2610312E17Rik antibody, C79984 antibody, p44/MEP50 antibody, RGD1310479 antibody, mep50 antibody, valois antibody, WDR77 antibody, zgc:65780 antibody, zgc:77274 antibody, WD repeat domain 77 antibody, WD repeat domain 77 S homeolog antibody, WDR77 antibody, Wdr77 antibody, wdr77.S antibody, wdr77 antibody
- 背景
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WDR77 is the non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. WDR77 might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.
Alias Symbols: HKMT1069, MEP50, MGC2722, Nbla10071, RP11-552M11.3, p44, MEP-50, p44/Mep50
Protein Interaction Partner: TP53, CUL3, SMAD1, AR, UBC, ASB15, WWOX, ZBTB1, SMYD1, COPS4, COPS7A, DCAF8, COPS8, PRMT5, TBC1D4, EPB41L2, HGS, FBXO6, PAN2, SNRPC, PPP1R8, POLR2C, PCBP2, HNRNPM, GRB2, QKI, TOE1, PPIL1, SAP30BP, LSM3, GPKOW, SF3A1, SF3B4, RBM5, PQBP1, THOC1, AQR, BAG2,
Protein Size: 342 - 分子量
- 38 kDa
- 基因ID
- 79084
- NCBI登录号
- NM_024102, NP_077007
- UniProt
- Q9BQA1
- 途径
- Ribonucleoprotein Complex Subunit Organization
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