alpha KGDHC 抗体 (N-Term)
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Quick Overview for alpha KGDHC 抗体 (N-Term) (ABIN2787780)
抗原
See all alpha KGDHC (alphaKGDHC) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MFHLRTCAAK LRPLTASQTV KTFSQNRPAA ARTFQQIRCY SAPVAAEPFL
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预测反应
- Cow: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against OGDH. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human OGDH
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anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (C-Term) antibody
alphaKGDHC 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) antibodyalphaKGDHC 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (N-Term) antibodyalphaKGDHC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (AA 41-423) antibodyalphaKGDHC 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (N-Term) antibodyalphaKGDHC 适用: 人, Cow, 马, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (N-Term) antibodyalphaKGDHC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (AA 256-582) antibodyalphaKGDHC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (AA 381-410), (C-Term) antibodyalphaKGDHC 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32469 unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) antibodyalphaKGDHC 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 427 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))
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别名
- OGDH
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背景
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The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitocondrial matrix and uses thiamine pyrophosphate as a cofactor. A congential deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia.
Alias Symbols: AKGDH, E1k, OGDC
Protein Interaction Partner: MDM2, UBC, SUMO1, NEDD8, CPSF7, MRPL38, MRPL41, TSR1, MRPS2, MRPL15, MRPL13, SCFD1, PDHX, SSBP1, SUMO2, PDHB, PDHA1, DLST, DLAT, DHODH, ISG15, USP13, PLSCR1, DLD,
Protein Size: 427 -
分子量
- 47 kDa
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基因ID
- 4967
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NCBI登录号
- NM_001003941, NP_001003941
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UniProt
- Q96DD3
抗原
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