MVP 抗体 (N-Term)
Quick Overview for MVP 抗体 (N-Term) (ABIN2787778)
抗原
See all MVP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MATEEFIIRI PPYHYIHVLD QNSNVSRVEV GPKTYIRQDN ERVLFAPMRM
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against MVP. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MVP
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anti-Major Vault Protein (MVP) (AA 1-893) antibody
MVP 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2H3-1A6 unconjugated
anti-Major Vault Protein (MVP) (AA 2-272) antibodyMVP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) antibodyMVP 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) antibodyKO Validated MVP 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) (AA 2-259) antibodyMVP 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, ELISA, IF, IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) antibodyMVP 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) (AA 88-180) antibodyMVP 适用: 人, 斑马鱼 FACS, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) antibodyMVP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) antibodyMVP 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal 1014 unconjugated
anti-Major Vault Protein (MVP) (C-Term) antibodyKO Validated MVP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 893 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MVP (Major Vault Protein (MVP))
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别名
- MVP
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背景
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MVP is required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. MVP down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. MVP down-regulates SRC activity and signaling through MAP kinases.This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences, however, the open reading frames are the same in both transcripts.
Alias Symbols: LRP, VAULT1
Protein Interaction Partner: MVP, SKIL, TRIM27, REL, PLSCR1, MEOX2, MEOX1, MDFI, KPNA3, GOLGA2, DLX2, CAMK2B, AES, TRIP6, TRAF2, TP53, TFCP2, TCF4, SUMO2, NOTCH2NL, CCDC36, TRIM42, FAM154A, PIH1D2, RAB3IP, RIMBP3, C1orf94, RHOXF2, ZMIZ2, OBFC1, RFWD2, MKL1, VAC14, BANP, FAM46C, KCTD9
Protein Size: 893 -
分子量
- 98 kDa
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基因ID
- 9961
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NCBI登录号
- NM_005115, NP_005106
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UniProt
- Q14764
抗原
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