FN3KRP 抗体 (N-Term)
(1 reference)Quick Overview for FN3KRP 抗体 (N-Term) (ABIN2787771)
抗原
See all FN3KRP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MDPGDPAGDP AAGERHRMGR DPLLLLQALQ TLWSTRERKQ LREEAWRGFA
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预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 93%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against FN3KRP. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human FN3KRP
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anti-Fructosamine 3 Kinase Related Protein (FN3KRP) (AA 24-58) antibody
FN3KRP 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB53014 unconjugated
anti-Fructosamine 3 Kinase Related Protein (FN3KRP) antibodyFN3KRP 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fructosamine 3 Kinase Related Protein (FN3KRP) (N-Term) antibodyFN3KRP 适用: 人, 大鼠, Cow, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Fructosamine 3 Kinase Related Protein (FN3KRP) (AA 1-309) antibodyFN3KRP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fructosamine 3 Kinase Related Protein (FN3KRP) antibodyFN3KRP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fructosamine 3 Kinase Related Protein (FN3KRP) (N-Term) antibodyFN3KRP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 309 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Fructosamine-3-kinase-related-protein phosphorylates glucitolamines on the C-4 hydroxyl: novel substrate specificity of an enigmatic enzyme." in: Biochemical and biophysical research communications, Vol. 361, Issue 4, pp. 870-5, (2007) (PubMed).
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: "Fructosamine-3-kinase-related-protein phosphorylates glucitolamines on the C-4 hydroxyl: novel substrate specificity of an enigmatic enzyme." in: Biochemical and biophysical research communications, Vol. 361, Issue 4, pp. 870-5, (2007) (PubMed).
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- FN3KRP (Fructosamine 3 Kinase Related Protein (FN3KRP))
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别名
- FN3KRP
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背景
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FN3KRP phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of the sugar moiety. Protein-bound psicosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions. Thus phosphorylation leads to deglycation.FN3KRP and FN3K (MIM 608425) protect proteins from nonenzymatic glycation by phosphorylating the modified amino acid. This phosphorylation destabilizes the sugar-amine linkage and leads to spontaneous decomposition (Conner et al., 2004 [PubMed 15381090]).[supplied by OMIM].
Alias Symbols: FLJ12171, FN3KL
Protein Interaction Partner: APP, CUL3, CUL4B, UBC, USP43,
Protein Size: 309 -
分子量
- 34 kDa
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基因ID
- 79672
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NCBI登录号
- NM_024619, NP_078895
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UniProt
- Q9HA64
抗原
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