PNPO 抗体 (N-Term)
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北京 101111
Quick Overview for PNPO 抗体 (N-Term) (ABIN2787718)
抗原
See all PNPO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- PNPO Antibody - N-terminal region
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序列
- PMRKSYRGDR EAFEETHLTS LDPVKQFAAW FEEAVQCPDI GEANAMCLAT
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预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against PNPO. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PNPO
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anti-Pyridoxamine 5'-Phosphate Oxidase (PNPO) (AA 1-261) antibody
PNPO 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxamine 5'-Phosphate Oxidase (PNPO) antibodyPNPO 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1G9 unconjugated
anti-Pyridoxamine 5'-Phosphate Oxidase (PNPO) antibodyPNPO 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxamine 5'-Phosphate Oxidase (PNPO) (AA 114-207) antibodyPNPO 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxamine 5'-Phosphate Oxidase (PNPO) antibodyPNPO 适用: 人, 大鼠, 犬, 猴 WB, IF 宿主: 小鼠 Monoclonal 3B3 unconjugated
anti-Pyridoxamine 5'-Phosphate Oxidase (PNPO) (AA 163-261) antibodyPNPO 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Pyridoxamine 5'-Phosphate Oxidase (PNPO) antibodyPNPO 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxamine 5'-Phosphate Oxidase (PNPO) antibodyKD Validated PNPO 适用: 人 WB 宿主: 小鼠 Monoclonal 25GB9480 unconjugated
anti-Pyridoxamine 5'-Phosphate Oxidase (PNPO) antibodyPNPO 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal AT2C7 unconjugated
anti-Pyridoxamine 5'-Phosphate Oxidase (PNPO) (AA 41-140) antibodyPNPO 适用: 人 WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58515-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Association between PNPO and schizophrenia in the Japanese population." in: Schizophrenia research, Vol. 97, Issue 1-3, pp. 264-70, (2007) (PubMed).
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- PNPO (Pyridoxamine 5'-Phosphate Oxidase (PNPO))
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别名
- PNPO
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背景
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Background Information: PNPO catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.Vitamin B6, or pyridoxal 5-prime-phosphate (PLP), is critical for normal cellular function, and some cancer cells have notable differences in vitamin B6 metabolism compared to their normal counterparts. The rate-limiting enzyme in vitamin B6 synthesis is pyridoxine-5-prime-phosphate (PNP) oxidase (PNPO, EC 1.4.3.5).[supplied by OMIM].
Gene Name: Pyridoxamine 5'-phosphate oxidase
Alternative Symbols: PDXPO, HEL-S-302
Protein Name: Pyridoxine-5'-phosphate oxidase
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分子量
- 29kDa
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基因ID
- 55163
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NCBI登录号
- NP_060599
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UniProt
- Q9NVS9
抗原
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