电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

PNPO 抗体 (N-Term)

Cited in 1 publication. The 兔 多克隆 anti-PNPO antibody (ABIN2787718) specifically detects PNPO in WB. The antibody is reactive with 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠 和 兔 samples.
产品编号 ABIN2787718
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PNPO 抗体 (N-Term) (ABIN2787718)

抗原

See all PNPO 抗体
PNPO (Pyridoxamine 5'-Phosphate Oxidase (PNPO))

适用

人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔

宿主

  • 37
  • 14

克隆类型

  • 39
  • 12
多克隆

标记

  • 29
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This PNPO antibody is un-conjugated

应用范围

  • 32
  • 19
  • 10
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 10
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    PMRKSYRGDR EAFEETHLTS LDPVKQFAAW FEEAVQCPDI GEANAMCLAT

    预测反应

    Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against PNPO. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human PNPO
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 261 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Song, Ueno, Numata, Iga, Shibuya-Tayoshi, Nakataki, Tayoshi, Yamauchi, Sumitani, Tomotake, Tada, Tanahashi, Itakura, Ohmori: "Association between PNPO and schizophrenia in the Japanese population." in: Schizophrenia research, Vol. 97, Issue 1-3, pp. 264-70, (2007) (PubMed).

  • 抗原

    PNPO (Pyridoxamine 5'-Phosphate Oxidase (PNPO))

    别名

    PNPO

    背景

    PNPO catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.Vitamin B6, or pyridoxal 5-prime-phosphate (PLP), is critical for normal cellular function, and some cancer cells have notable differences in vitamin B6 metabolism compared to their normal counterparts. The rate-limiting enzyme in vitamin B6 synthesis is pyridoxine-5-prime-phosphate (PNP) oxidase (PNPO, EC 1.4.3.5).[supplied by OMIM].
    Alias Symbols: FLJ10535, PDXPO
    Protein Interaction Partner: UBC, LPP, APP, ELAVL1,
    Protein Size: 261

    分子量

    29 kDa

    基因ID

    55163

    NCBI登录号

    NM_018129, NP_060599

    UniProt

    Q9NVS9
You are here: