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GPX4 抗体 (Middle Region)

This anti-GPX4 antibody is a 兔 多克隆 antibody detecting GPX4 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 斑马鱼, 豚鼠, Cow, 山羊 和 Saccharomyces cerevisiae.
产品编号 ABIN2787700
发货至: 中国

Quick Overview for GPX4 抗体 (Middle Region) (ABIN2787700)

抗原

See all GPX4 抗体
GPX4 (Glutathione Peroxidase 4 (GPX4))

适用

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人, 小鼠, 大鼠, 斑马鱼, 豚鼠, Cow, 山羊, Saccharomyces cerevisiae

宿主

  • 61
  • 16
  • 1

克隆类型

  • 48
  • 30
多克隆

标记

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  • 2
  • 2
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  • 2
  • 1
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This GPX4 antibody is un-conjugated

应用范围

  • 43
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 11
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    QUGKTEVNYT QLVDLHARYA ECGLRILAFP CNQFGKQEPG SNEEIKEFAA

    预测反应

    Cow: 86%, Goat: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Rat: 86%, Yeast: 93%, Zebrafish: 86%

    产品特性

    This is a rabbit polyclonal antibody against GPX4. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human GPX4
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 197 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    GPX4 (Glutathione Peroxidase 4 (GPX4))

    别名

    GPX4

    背景

    Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists, alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists, alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.
    Alias Symbols: MCSP, PHGPx, snGPx, snPHGPx
    Protein Interaction Partner: UBC, PRDX6, MAPK13, OTUD5,
    Protein Size: 197

    分子量

    22 kDa

    基因ID

    2879

    NCBI登录号

    NM_002085, NP_002076

    UniProt

    P36969
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