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GLP2R 抗体 (N-Term)

This anti-GLP2R antibody is a 兔 多克隆 antibody detecting GLP2R in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2787698
发货至: 中国

Quick Overview for GLP2R 抗体 (N-Term) (ABIN2787698)

抗原

See all GLP2R 抗体
GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))

适用

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宿主

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克隆类型

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多克隆

标记

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This GLP2R antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    KLGSSRAGPG RGSAGLLPGV HELPMGIPAP WGTSPLSFHR KCSLWAPGRP

    预测反应

    Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against GLP2R. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human GLP2R
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 553 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Sams, Hastrup, Andersen, Thim: "Naturally occurring glucagon-like peptide-2 (GLP-2) receptors in human intestinal cell lines." in: European journal of pharmacology, Vol. 532, Issue 1-2, pp. 18-23, (2006) (PubMed).

  • 抗原

    GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))

    别名

    GLP2R

    背景

    The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R).
    Alias Symbols: -
    Protein Interaction Partner: UBC, GCG, CALM1,
    Protein Size: 553

    分子量

    61 kDa

    基因ID

    9340

    NCBI登录号

    NM_004246, NP_004237

    UniProt

    O95838

    途径

    Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Feeding Behaviour
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