TINF2 抗体 (Middle Region)
Quick Overview for TINF2 抗体 (Middle Region) (ABIN2787641)
抗原
See all TINF2 (TIN2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- SDEEENGQGE GKESLENYQK TKFDTLIPTL CEYLPPSGHG AIPVSSCDCR
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预测反应
- Cow: 100%, Dog: 86%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 85%
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产品特性
- This is a rabbit polyclonal antibody against TINF2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TINF2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 451 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))
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别名
- TINF2
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背景
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TINF2 is a component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. It plays a role in shelterin complex assembly.
Alias Symbols: TIN2, DKCA3
Protein Interaction Partner: ACD, TERF2, TPP1, ANXA8L1, TNKS, TERF1, VIPR1, ZNF790, PAGE2, TUBB, DHFRL1, APOBEC3F, REM2, NUDCD2, CCDC43, SCRN2, TRIM15, TXNDC17, AFAP1L2, FERMT3, KCTD17, ANKMY2, PPP6R3, PGM2, APPL2, BIN2, LGALSL, PHPT1, GNMT, OR2H1, CCDC9, POT1, AIPL1, NCDN, ACOT7, TO
Protein Size: 451 -
分子量
- 50 kDa
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基因ID
- 26277
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NCBI登录号
- NM_001099274, NP_001092744
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UniProt
- Q9BSI4
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途径
- Cell Division Cycle, Telomere Maintenance, Regulation of Carbohydrate Metabolic Process
抗原
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