POT1 抗体 (Middle Region)
Quick Overview for POT1 抗体 (Middle Region) (ABIN2787632)
抗原
See all POT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- MNSENQTMLS LEFHLHGGTS YGRGIRVLPE SNSDVDQLKK DLESANLTAN
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预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against POT1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human POT1
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anti-Protection of Telomeres 1 (POT1) (AA 250-432) antibody
POT1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protection of Telomeres 1 (POT1) (AA 1-95) antibodyPOT1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protection of Telomeres 1 (POT1) (AA 497-634) antibodyPOT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protection of Telomeres 1 (POT1) (AA 251-300) antibodyPOT1 适用: 人, 小鼠, 豚鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Protection of Telomeres 1 (POT1) (Internal Region) antibodyPOT1 适用: 人, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protection of Telomeres 1 (POT1) (N-Term) antibodyPOT1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protection of Telomeres 1 (POT1) (AA 251-300) antibodyPOT1 适用: 人, 豚鼠, 犬, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 634 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- POT1 (Protection of Telomeres 1 (POT1))
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别名
- POT1
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背景
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This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
Alias Symbols: DKFZP586D211, hPot1, HPOT1
Protein Interaction Partner: TPP1, CFL2, ACD, CORO1A, KHDRBS1, LAMC3, BCAS2, MVP, ZNF32, ECI1, CSNK2B, COX6A2, ALDH1A1, ACTN4, SERTAD1, C2orf74, ZBTB49, ZBED2, CYP4F11, MYO5C, RIF1, NAP1L1, MDM2, KRT18, GRN, PACSIN1, SULT4A1, PGLS, AIPL1, SH3BP1, HAAO, NCDN, TWF2, ACOT7, DDX19B, PACS
Protein Size: 634 -
分子量
- 70 kDa
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基因ID
- 25913
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NCBI登录号
- NM_015450, NP_056265
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UniProt
- Q9NUX5
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途径
- Cell Division Cycle, Telomere Maintenance
抗原
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