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KDM4B 抗体 (Middle Region)

This anti-KDM4B antibody is a 兔 多克隆 antibody detecting KDM4B in WB. Suitable for 人, 小鼠, 大鼠, 犬, 马, Pig, Cow 和 豚鼠.
产品编号 ABIN2787592
发货至: 中国

Quick Overview for KDM4B 抗体 (Middle Region) (ABIN2787592)

抗原

See all KDM4B 抗体
KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

适用

人, 小鼠, 大鼠, 犬, 马, Pig, Cow, 豚鼠

宿主

  • 67
  • 4

克隆类型

  • 65
  • 6
多克隆

标记

  • 35
  • 7
  • 6
  • 6
  • 6
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KDM4B antibody is un-conjugated

应用范围

  • 51
  • 44
  • 17
  • 15
  • 14
  • 7
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 8
    • 7
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    SASRASLKAK LLRRSHRKRS QPKKPKPEDP KFPGEGTAGA ALLEEAGGSV

    预测反应

    Cow: 92%, Dog: 93%, Guinea Pig: 83%, Horse: 93%, Human: 100%, Mouse: 82%, Pig: 93%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against JMJD2B. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human JMJD2B
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1096 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

    别名

    JMJD2B

    背景

    JMJD2 family proteins are classified into one group with JD2H and TUDOR domains and another group without JD2H or TUDOR domains. Because JMJD2C gene (also known as GASC1 gene) is amplified in esophageal squamous cell carcinoma (ESCC), JMJD2 family genes are cancer-associated genes. Human genes corresponding to KIAA0677, KIAA0876, KIAA0780 and FLJ10251 cDNAs were designated JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively. In addition, JMJD2D homologous genes within human genome sequences AP002383.3 and AP001264.4 were designated JMJD2E and JMJD2F, respectively. C2HC2HC2- and C5HC2-type Cys (His) clusters were identified as the region conserved among JMJD2A (1064 aa), JMJD2B (1096 aa), and JMJD2C (1056 aa) proteins. JMJD2A, JMJD2B and JMJD2C consist of JmjN, JmjC, JD2H, and two TUDOR domains.
    Alias Symbols: FLJ44906, KDM4B, KIAA0876, JMJD2B
    Protein Interaction Partner: UBC, H3F3C, HSP90B1, HSP90AA2P, SMU1, KMT2C, WDR5, ASH2L, KMT2D, RBBP5, HSPA4, HNRNPU, ESR1, MED10,
    Protein Size: 1096

    分子量

    122 kDa

    基因ID

    23030

    NCBI登录号

    NM_015015, NP_055830

    UniProt

    O94953

    途径

    Warburg Effect
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