RORC encodes a protein which is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that RORC may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Alias Symbols: NR1F3, RORG, RZR-GAMMA, RZRG, TOR Protein Interaction Partner: EVI2A, NCOA6, EIF3I, CHD4, EIF4EBP1, Protein Size: 518