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UBE2K 抗体 (N-Term)

There is 1 publication for this product available. The 兔 多克隆 anti-UBE2K antibody is suitable to detect UBE2K in samples from 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 山羊, 马, 兔, 豚鼠 和 Saccharomyces cerevisiae. It has been validated for WB.
产品编号 ABIN2787510
发货至: 中国
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Quick Overview for UBE2K 抗体 (N-Term) (ABIN2787510)

抗原

See all UBE2K 抗体
UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

适用

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人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 山羊, 马, 兔, 豚鼠, Saccharomyces cerevisiae

宿主

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克隆类型

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多克隆

标记

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This UBE2K antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    FTELRGEIAG PPDTPYEGGR YQLEIKIPET YPFNPPKVRF ITKIWHPNIS

    预测反应

    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against UBE2K. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2K
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 200 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Fromm-Dornieden, von der Heyde, Lytovchenko, Salinas-Riester, Brenig, Beissbarth, Baumgartner: "Novel polysome messages and changes in translational activity appear after induction of adipogenesis in 3T3-L1 cells." in: BMC molecular biology, Vol. 13, pp. 9, (2012) (PubMed).

  • 抗原

    UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

    别名

    UBE2K

    背景

    UBE2K belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation.The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.
    Alias Symbols: DKFZp564C1216, DKFZp686J24237, E2-25K, HIP2, HYPG, LIG, UBC1
    Protein Interaction Partner: DDI1, DTX3, MIPOL1, TRIM39, ANAPC11, RNF138, SIAH1, RNF5, REL, FZR1, UBC, UBA1, MARCH7, AMFR, TP53, MDM2, BAG3, PRRG4, IQCB1, HTT, CDC6, WDR1, TYMS, TXN, TXNDC17, WDR61, ITCH, NEDD4L, WWP2, NXF1, NUB1, PIAS4, CASP12, SUMO1, SUMO2, DIABLO, UBE2I, CCNB1, BR
    Protein Size: 200

    分子量

    22 kDa

    基因ID

    3093

    NCBI登录号

    NM_005339, NP_005330

    UniProt

    P61086
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