CEBPA 抗体 (C-Term)
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北京 101111
Quick Overview for CEBPA 抗体 (C-Term) (ABIN2787466)
抗原
See all CEBPA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- CEBPA Antibody - C-terminal region
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序列
- ASGGSGAGKA KKSVDKNSNE YRVRRERNNI AVRKSRDKAK QRNVETQQKV
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against CEBPA. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CEBPA
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57938-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))
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别名
- CEBPA
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背景
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Background Information: CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
Gene Name: CCAAT/enhancer binding protein (C/EBP), alpha
Alternative Symbols: CEBP, C/EBP-alpha
Protein Name: CCAAT/enhancer-binding protein alpha
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分子量
- 37kDa
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基因ID
- 1050
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NCBI登录号
- NP_004355
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UniProt
- P49715
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途径
- Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
抗原
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