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CEBPA 抗体 (Middle Region)

Name: CEBPA 抗体 (Middle Region)
SKU: ABIN2787465
Availability: OutOfStock

This anti-CEBPA antibody is a 兔多克隆 antibody detecting CEBPA in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 斑马鱼, 豚鼠, 犬, 兔, 马和绵羊. This Primary Antibody has been cited in 2+ publications.

WB Suggested Anti-CEBPA Antibody Titration: 0. (CEBPA 抗体 (Middle Region))

Immunohistochemistry (IHC) image for anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (Middle Region) antibody (ABIN2787465) (CEBPA 抗体 (Middle Region))

IHC

3 images

(2 references)

产品编号 ABIN2787465

发货至: 中国

Quick Overview for CEBPA 抗体 (Middle Region) (ABIN2787465)

抗原

See all CEBPA 抗体

CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

适用

人, 小鼠, 大鼠, Cow, 斑马鱼, 豚鼠, 犬, 兔, 马, 绵羊

宿主

兔

克隆类型

多克隆

标记

This CEBPA antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product CEBPA Primary Antibody

抗原表位
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12

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9

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1

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1

1

1

1

1

1

1

1

1

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1

1

1

1

1

1

1
Middle Region

序列

RRERNNIAVR KSRDKAKQRN VETQQKVLEL TSDNDRLRKR VEQLSRELDT

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 79%, Zebrafish: 93%

产品特性

This is a rabbit polyclonal antibody against CEBPA. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human CEBPA
anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) antibody
CEBPA 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5B7 unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) antibody
CEBPA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (pSer21) antibody
CEBPA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (AA 1-205) antibody
CEBPA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (pThr226) antibody
CEBPA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (AA 288-337) antibody
CEBPA 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, Pig, 犬, 兔, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (N-Term) antibody
CEBPA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (N-Term) antibody
KO Validated CEBPA 适用: 人 WB, IHC (p), IP, ChIP 宿主: 兔 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) antibody
CEBPA 适用: 人 WB, FACS, EIA 宿主: 小鼠 Monoclonal 4-00E-010 unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (AA 1-124) antibody
CEBPA 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 358 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Miglino, Roth, Tamm, Borger: "House dust mite extract downregulates C/EBP? in asthmatic bronchial smooth muscle cells." in: The European respiratory journal, Vol. 38, Issue 1, pp. 50-8, (2011) (PubMed).

Borger, Miglino, Baraket, Black, Tamm, Roth: "Impaired translation of CCAAT/enhancer binding protein alpha mRNA in bronchial smooth muscle cells of asthmatic patients." in: The Journal of allergy and clinical immunology, Vol. 123, Issue 3, pp. 639-45, (2009) (PubMed).
抗原

CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

别名

CEBPA

背景

CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2385 U34070.1 592-2976
Alias Symbols: C/EBP-alpha, CEBP
Protein Interaction Partner: CEBPB, ZBTB16, RARA, HDAC1, BHLHE41, UBC, CEBPE, BATF2, BATF3, YY1AP1, ATF5, BATF, FOSL1, FOS, DBP, CEBPG, CEBPA, ATF4, ATF3, UBE3A, SKP2, RASGRF1, C1QBP, CDKN1A, SRA1, CDK4, PIAS1, Fbxw7, GRIN3A, RAB34, NAA16, POLR1E, MRTO4, AK5, MACF1, KAT5, AKAP9, SMC1
Protein Size: 358

分子量

37 kDa

基因ID

1050

NCBI登录号

NM_004364, NP_004355

UniProt

P49715

途径

Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation