MED16 抗体 (Middle Region)
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北京 101111
Quick Overview for MED16 抗体 (Middle Region) (ABIN2787461)
抗原
See all MED16 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- IVALSWLHNG VKLALHVEKS GASSFGEKFS RVKFSPSLTL FGGKPMEGWI
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against MED16. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human MED16
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MED16 (Mediator Complex Subunit 16 (MED16))
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别名
- MED16
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背景
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MED16 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. It mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Protein Interaction Partner: HECW2, CDK19, CDK8, UBC, MED19, MED26, EPAS1, FBXW7, MED11, MED8, MED29, MED9, MED18, MED4, RALY, MED13, MED12, MED24, MED21, MED14, MED1, CTDP1, HIST1H3A, MED10, MED25, MED15, VDR, TRA, MED28, OBFC1, ZC3H13, QKI, TADA2A, SUPT7L, SUPT3H, MYC, KAT2A, TRRAP
Protein Size: 663 -
分子量
- 72 kDa
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基因ID
- 10025
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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