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RCAN1 抗体 (N-Term)

This anti-RCAN1 antibody is a 兔 多克隆 antibody detecting RCAN1 in WB. Suitable for 人, 小鼠, 大鼠 和 犬.
产品编号 ABIN2787429
发货至: 中国

Quick Overview for RCAN1 抗体 (N-Term) (ABIN2787429)

抗原

See all RCAN1 抗体
RCAN1 (Regulator of Calcineurin 1 (RCAN1))

适用

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人, 小鼠, 大鼠, 犬

宿主

  • 70
  • 5
  • 1

克隆类型

  • 73
  • 3
多克隆

标记

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  • 1
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This RCAN1 antibody is un-conjugated

应用范围

  • 59
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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    MEDGVAGPQL GAAAEAAEAA EARARPGVTL RPFAPLSGAA EADEGGGDWS

    预测反应

    Dog: 93%, Human: 100%, Mouse: 77%, Rat: 92%

    产品特性

    This is a rabbit polyclonal antibody against RCAN1. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human RCAN1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 252 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    RCAN1 (Regulator of Calcineurin 1 (RCAN1))

    别名

    RCAN1

    背景

    RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
    Alias Symbols: ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1
    Protein Interaction Partner: UBC, PPP3CA, NEDD8, APP, FBXW11, BTRC, FBXW4, TOLLIP, TRAF6, IRAK1, HSP90AA1, STAT2, GSK3B, MAP3K3, MAPK3, UXT,
    Protein Size: 252

    分子量

    28 kDa

    基因ID

    1827

    NCBI登录号

    NM_004414, NP_004405

    UniProt

    P53805

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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