RCAN1 抗体 (N-Term)
Quick Overview for RCAN1 抗体 (N-Term) (ABIN2787429)
抗原
See all RCAN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MEDGVAGPQL GAAAEAAEAA EARARPGVTL RPFAPLSGAA EADEGGGDWS
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预测反应
- Dog: 93%, Human: 100%, Mouse: 77%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against RCAN1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RCAN1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 252 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
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别名
- RCAN1
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背景
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RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
Alias Symbols: ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1
Protein Interaction Partner: UBC, PPP3CA, NEDD8, APP, FBXW11, BTRC, FBXW4, TOLLIP, TRAF6, IRAK1, HSP90AA1, STAT2, GSK3B, MAP3K3, MAPK3, UXT,
Protein Size: 252 -
分子量
- 28 kDa
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基因ID
- 1827
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NCBI登录号
- NM_004414, NP_004405
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UniProt
- P53805
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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